SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00530

Signal sequence   MMPSRTNLATGIPSSKVKYSRLSSTDDGYIDLQFKKTPPKIPYKAIALATVLFLIGA

Length  57

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..57



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00530.cif

Structure  SPKB00530.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6216.34804

Aliphatic index  94.21052632

Isoelectric point  10.46553217

Charge (pH=7)   4.994995683

Topological polar surface area  2410.19

Aromaticity  0.087719298

Average rotatable bonds  3.543859649

Number of hydrogen bond donors  84

Number of hydrogen bond acceptors  87

X logP energy  -21.54926

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.