SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00528

Signal sequence   METVVIVAIGVLATIFLASFAALVLVCRQ

Length  29

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00528.cif

Structure  SPKB00528.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3048.77924

Aliphatic index  171.3793103

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  1081.1

Aromaticity  0.068965517

Average rotatable bonds  3.379310345

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  38

X logP energy  -4.72193

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.