SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00523

Signal sequence   MATPNNLTPTNCSWWPISALESDAAKPAEAPDAPEAASPAHWPRESLVLYHWTQSFSSQKAKILEHDDVSYLKKILGELAMVLDQIEADLEKRKLENEGQKCELWLCGCEFTLADVLLGATLHRLKFLGLSKKYWEDGSRPNLQSFFERVQRRFAFRKVLGDIHTTLLSAVIPNAFRLVKRKPPSFFGASFLMGSLG

Length  197

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..197



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00523.cif

Structure  SPKB00523.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  22204.56694

Aliphatic index  86.75126904

Isoelectric point  7.979019267

Charge (pH=7)   1.226786136

Topological polar surface area  8804.05

Aromaticity  0.101522843

Average rotatable bonds  3.695431472

Number of hydrogen bond donors  307

Number of hydrogen bond acceptors  296

X logP energy  -101.9752

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.