SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00518

Signal sequence   MATPNNLTPTNCSWWPISALESDAAKPAEAPDAPEAASPAHWPRESLVLYHWTQSFSSQKAKILEHDDVSYLKKILGELAMVLDQIEAALEKRKLENEGQKCELWLCGCDFTLADVLLGATLHRLKFLGLSKKYWEDGSRPNLQSFFERVQRRFAFRKVLGDIHTTLLSAVIPNAFRLVKRKPPSFFGASFLMGSLG

Length  197

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..197



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00518.cif

Structure  SPKB00518.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  22146.53024

Aliphatic index  87.25888325

Isoelectric point  8.334168677

Charge (pH=7)   2.225011014

Topological polar surface area  8766.75

Aromaticity  0.101522843

Average rotatable bonds  3.680203046

Number of hydrogen bond donors  306

Number of hydrogen bond acceptors  295

X logP energy  -101.6971

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.