SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00516

Signal sequence   MEKPLFPLVPLHWFGFGYTALVVSGGIVGYVKTGSVPSLAAGLLFGSLA

Length  49

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..49



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00516.cif

Structure  SPKB00516.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5066.03464

Aliphatic index  115.3061224

Isoelectric point  9.124256358

Charge (pH=7)   1.088377617

Topological polar surface area  1720.61

Aromaticity  0.142857143

Average rotatable bonds  3.12244898

Number of hydrogen bond donors  59

Number of hydrogen bond acceptors  63

X logP energy  -8.6609

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.