SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00515

Signal sequence   MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHCVRDTYHRERVWGFYRGLSLPVCTVSLVSS

Length  68

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..68



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00515.cif

Structure  SPKB00515.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7518.71764

Aliphatic index  91.47058824

Isoelectric point  8.48790964

Charge (pH=7)   1.99475975

Topological polar surface area  2929.71

Aromaticity  0.117647059

Average rotatable bonds  3.455882353

Number of hydrogen bond donors  109

Number of hydrogen bond acceptors  101

X logP energy  -24.88445

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.