SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00514

Signal sequence   MVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLVDLAILGQAYA

Length  45

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..45



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00514.cif

Structure  SPKB00514.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4864.83984

Aliphatic index  125.7777778

Isoelectric point  6.265217978

Charge (pH=7)   -0.065388344

Topological polar surface area  1728.01

Aromaticity  0.133333333

Average rotatable bonds  3.466666667

Number of hydrogen bond donors  60

Number of hydrogen bond acceptors  62

X logP energy  -8.4995

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.