SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00511

Signal sequence   MVSALRGAPLIRVHSSPVSSPSVSGPRRLVSCLSSQSSALS

Length  41

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..41



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00511.cif

Structure  SPKB00511.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4164.81144

Aliphatic index  99.75609756

Isoelectric point  12.50009851

Charge (pH=7)   4.026905429

Topological polar surface area  1774.52

Aromaticity  0

Average rotatable bonds  3.219512195

Number of hydrogen bond donors  66

Number of hydrogen bond acceptors  63

X logP energy  -26.43862

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.