SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00510

Signal sequence   MSFFQLLMKRKELIPLVVFMTVAAGGASS

Length  29

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00510.cif

Structure  SPKB00510.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3172.89614

Aliphatic index  107.5862069

Isoelectric point  10.7890093

Charge (pH=7)   1.999166043

Topological polar surface area  1144.58

Aromaticity  0.103448276

Average rotatable bonds  3.655172414

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  42

X logP energy  -7.00343

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.