SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00509

Signal sequence   MATPPFRLIRKMFSFKVSRWMGLACFRSLAAS

Length  32

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00509.cif

Structure  SPKB00509.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3707.53824

Aliphatic index  70.3125

Isoelectric point  12.5164677

Charge (pH=7)   5.935406271

Topological polar surface area  1364.42

Aromaticity  0.15625

Average rotatable bonds  3.71875

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  48

X logP energy  -9.46412

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.