SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00508

Signal sequence   MVLTKPLQRNGSMMSFENVKEKSREGGPHAHTPEEELCFVVTHYPQVQTTLNLFFHIFKVLTQPLSLLWG

Length  70

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..70



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00508.cif

Structure  SPKB00508.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  8069.36994

Aliphatic index  82

Isoelectric point  7.683783493

Charge (pH=7)   0.308259511

Topological polar surface area  3133.62

Aromaticity  0.1

Average rotatable bonds  3.742857143

Number of hydrogen bond donors  106

Number of hydrogen bond acceptors  109

X logP energy  -25.56536

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.