SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00507

Signal sequence   MSCSLKFTLIVIFFYCWLSSS

Length  21

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00507.cif

Structure  SPKB00507.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2476.00424

Aliphatic index  106.6666667

Isoelectric point  8.221165971

Charge (pH=7)   0.872889419

Topological polar surface area  828.74

Aromaticity  0.238095238

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -3.5348

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.