SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00506

Signal sequence   MKPLLVVFVFLFLWDPVLA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00506.cif

Structure  SPKB00506.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2247.85314

Aliphatic index  168.9473684

Isoelectric point  6.337367167

Charge (pH=7)   -0.00186425

Topological polar surface area  648.65

Aromaticity  0.210526316

Average rotatable bonds  3.473684211

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  23

X logP energy  4.8204

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.