SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00505

Signal sequence   MKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADA

Length  46

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..46



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00505.cif

Structure  SPKB00505.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4851.44604

Aliphatic index  87.17391304

Isoelectric point  3.446775223

Charge (pH=7)   -6.119999276

Topological polar surface area  1924.68

Aromaticity  0.086956522

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  65

Number of hydrogen bond acceptors  69

X logP energy  -19.8026

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.