SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00504

Signal sequence   MPCLDQQLTVHALPCPAQPSSLAFCQVGFLTA

Length  32

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00504.cif

Structure  SPKB00504.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3387.99264

Aliphatic index  91.5625

Isoelectric point  5.285195117

Charge (pH=7)   -1.096584273

Topological polar surface area  1249.52

Aromaticity  0.0625

Average rotatable bonds  3.15625

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  47

X logP energy  -12.018

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.