SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00500

Signal sequence   MKAPGRLVLIILCSVVFS

Length  18

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00500.cif

Structure  SPKB00500.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1946.48344

Aliphatic index  162.2222222

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  677.61

Aromaticity  0.055555556

Average rotatable bonds  3.5

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -2.70163

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.