SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00491

Signal sequence   MKLKTVRSAVLSSLFASQVLG

Length  21

Organism  Saccharomyces cerevisiae

UniProt ID  P32329,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  MI3 yield: 120%

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00491.cif

Structure  SPKB00491.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2235.71364

Aliphatic index  125.2380952

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  903.5

Aromaticity  0.047619048

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -8.94953

Hydropathy 



Literature Information


Title  DNA construct encoding the YAP3 signal peptide

DOI  NA,

Publication Year  1998

PubMed ID  NA,

Patent ID  US5726038A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.