SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00490

Signal sequence   RFSTTLATAATALFFTASQVSA

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00490.cif

Structure  SPKB00490.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2262.54754

Aliphatic index  75.90909091

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  941.25

Aromaticity  0.136363636

Average rotatable bonds  3.136363636

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  33

X logP energy  -12.41553

Hydropathy 



Literature Information


Title  Application of novel DNA fragments as a coding sequence for a signal peptide for the secretion of mature proteins by recombinant yeast, expression cassettes, transformed yeast and corresponding process for the preparation of proteins

DOI  NA,

Publication Year  1997

PubMed ID  NA,

Patent ID  US5631144A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.