SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00487

Signal sequence   RFSTTVATAATALFFTASQ

Length  19

Organism  Artificial

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00487.cif

Structure  SPKB00487.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1991.23114

Aliphatic index  62.10526316

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  833.72

Aromaticity  0.157894737

Average rotatable bonds  3.157894737

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  29

X logP energy  -10.92823

Hydropathy 



Literature Information


Title  Application of novel DNA fragments as a coding sequence for a signal peptide for the secretion of mature proteins by recombinant yeast, expression cassettes, transformed yeast and corresponding process for the preparation of proteins

DOI  NA,

Publication Year  1997

PubMed ID  NA,

Patent ID  US5631144A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.