General Information
SPKB ID SPKB00484
Signal sequence MKVLLRLICFIALLISS
Length 17
Organism Homo sapiens (Human)
UniProt ID P14778,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00484.cif
Physicochemical Information
Molecular weight 1933.52784
Aliphatic index 206.4705882
Isoelectric point 9.833242293
Charge (pH=7) 1.935711238
Topological polar surface area 657.3
Aromaticity 0.058823529
Average rotatable bonds 3.882352941
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 24
X logP energy -0.49773
Hydropathy
Literature Information
Title Expression system comprising mutant yeast strain and expression vector encoding synthetic signal peptide
DOI NA,
Publication Year 1996
PubMed ID NA,
Patent ID US5538863A,