SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00483

Signal sequence   MKVLLRLICFIALLLGTALA

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00483.cif

Structure  SPKB00483.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2172.84544

Aliphatic index  205

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  724.37

Aromaticity  0.05

Average rotatable bonds  3.65

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  26

X logP energy  0.07017

Hydropathy 



Literature Information


Title  Expression system comprising mutant yeast strain and expression vector encoding synthetic signal peptide

DOI  NA,

Publication Year  1996

PubMed ID  NA,

Patent ID  US5538863A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.