SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00481

Signal sequence   MKVLLGLICLMVLGTALA

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00481.cif

Structure  SPKB00481.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1859.46084

Aliphatic index  195

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  604.27

Aromaticity  0

Average rotatable bonds  3.5

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  -0.477

Hydropathy 



Literature Information


Title  Expression system comprising mutant yeast strain and expression vector encoding synthetic signal peptide

DOI  NA,

Publication Year  1996

PubMed ID  NA,

Patent ID  US5538863A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.