SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00478

Signal sequence   MRSLLLLLLLLLLPGCWA

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Human serum albumin: 40ug/mL

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00478.cif

Structure  SPKB00478.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2038.66694

Aliphatic index  222.2222222

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  647.15

Aromaticity  0.055555556

Average rotatable bonds  3.611111111

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  1.92087

Hydropathy 



Literature Information


Title  DNA's encoding signal peptides

DOI  NA,

Publication Year  1995

PubMed ID  NA,

Patent ID  US5409815A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.