General Information
SPKB ID SPKB00476
Signal sequence MKSTLLLLFLLLCLPSWNAGA
Length 21
Organism Artificial
UniProt ID NA,
Motif 1..21
Activity Information
Pathway NA
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency Hirudin Variant: 3.1mg/L
Type NA
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00476.cif
Physicochemical Information
Molecular weight 2304.87724
Aliphatic index 158.0952381
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 782.12
Aromaticity 0.095238095
Average rotatable bonds 3.476190476
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 29
X logP energy -2.3401
Hydropathy 
Literature Information
Title Signal peptide, DNA sequences coding for the latter, expression vectors carrying one of these sequences, gram-negative bacteria transformed by these vectors, and process for the periplasmic production of a polypeptide
DOI NA,
Publication Year 1994
PubMed ID NA,
Patent ID US5284768A,
