SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00459

Signal sequence   MKLWFSTLKLKKAAAVLLFSCVALAGSANNQTNA

Length  34

Organism  Artificial

UniProt ID  NA,

Motif  1..34



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Human growth hormone: 4350ng/OD600

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00459.cif

Structure  SPKB00459.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3611.32144

Aliphatic index  106.4705882

Isoelectric point  10.80483506

Charge (pH=7)   3.934829448

Topological polar surface area  1417

Aromaticity  0.088235294

Average rotatable bonds  3.558823529

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  50

X logP energy  -13.2055

Hydropathy 



Literature Information


Title  Modified signal peptides

DOI  NA,

Publication Year  1987

PubMed ID  NA,

Patent ID  US4711844A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.