SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00454

Signal sequence   MTRLTVLALLAGLLASSRA

Length  19

Organism  Artificial

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00454.cif

Structure  SPKB00454.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1957.40554

Aliphatic index  159.4736842

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  791.84

Aromaticity  0

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  27

X logP energy  -7.20586

Hydropathy 



Literature Information


Title  Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN119040362A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.