SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00448

Signal sequence   MALTFALLVALLVLSCKSSCSVG

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00448.cif

Structure  SPKB00448.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2326.89654

Aliphatic index  152.6086957

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  830.69

Aromaticity  0.043478261

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -6.666

Hydropathy 



Literature Information


Title  Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN119040362A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.