General Information
SPKB ID SPKB00447
Signal sequence MALPVTALLLPLALLLHAARP
Length 21
Organism Artificial
UniProt ID NA,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8EK5,
Predicted Structure ID SPKB00447.cif
Physicochemical Information
Molecular weight 2194.79344
Aliphatic index 186.1904762
Isoelectric point 10.5517587
Charge (pH=7) 1.088890079
Topological polar surface area 729.76
Aromaticity 0
Average rotatable bonds 3.095238095
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 26
X logP energy -0.89983
Hydropathy
Literature Information
Title Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof
DOI NA,
Publication Year 2024
PubMed ID NA,
Patent ID CN119040362A,