SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00444

Signal sequence   MRMQLLLLIALSLALVTNS

Length  19

Organism  Artificial

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00444.cif

Structure  SPKB00444.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2100.64934

Aliphatic index  190

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  795.89

Aromaticity  0

Average rotatable bonds  3.789473684

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -4.53493

Hydropathy 



Literature Information


Title  Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN119040362A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.