General Information
SPKB ID SPKB00443
Signal sequence MDAMKRGLCCVLLLCGAVFVSP
Length 22
Organism Artificial
UniProt ID NA,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 5VN3,
Predicted Structure ID SPKB00443.cif
Physicochemical Information
Molecular weight 2326.93534
Aliphatic index 119.5454545
Isoelectric point 8.045811842
Charge (pH=7) 0.812208291
Topological polar surface area 811.08
Aromaticity 0.045454545
Average rotatable bonds 3.409090909
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 32
X logP energy -5.06213
Hydropathy
Literature Information
Title Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof
DOI NA,
Publication Year 2024
PubMed ID NA,
Patent ID CN119040362A,