General Information
SPKB ID SPKB00441
Signal sequence MDMRVPAQLLGLLLLWLSGARC
Length 22
Organism Artificial
UniProt ID NA,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8JBV,
Predicted Structure ID SPKB00441.cif
Physicochemical Information
Molecular weight 2457.05144
Aliphatic index 146.3636364
Isoelectric point 8.54983383
Charge (pH=7) 0.936449445
Topological polar surface area 905.84
Aromaticity 0.045454545
Average rotatable bonds 3.636363636
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 31
X logP energy -4.21436
Hydropathy
Literature Information
Title Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof
DOI NA,
Publication Year 2024
PubMed ID NA,
Patent ID CN119040362A,