General Information
SPKB ID SPKB00439
Signal sequence METDTLLLWVLLLWVPGSTGAA
Length 22
Organism Artificial
UniProt ID NA,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 4KUC,
Predicted Structure ID SPKB00439.cif
Physicochemical Information
Molecular weight 2386.83154
Aliphatic index 141.8181818
Isoelectric point 3.550073557
Charge (pH=7) -1.999794094
Topological polar surface area 852.73
Aromaticity 0.090909091
Average rotatable bonds 3.272727273
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 30
X logP energy -3.3482
Hydropathy
Literature Information
Title Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof
DOI NA,
Publication Year 2024
PubMed ID NA,
Patent ID CN119040362A,