SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00438

Signal sequence   MWWRLWWLLLLLLLLWGSSASAA

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00438.cif

Structure  SPKB00438.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2786.41884

Aliphatic index  165.6521739

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  905.06

Aromaticity  0.217391304

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  29

X logP energy  2.78317

Hydropathy 



Literature Information


Title  Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN119040362A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.