SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00435

Signal sequence   MKPIFLVLLVATSAYA

Length  16

Organism  Artificial

UniProt ID  NA,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00435.cif

Structure  SPKB00435.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1737.17374

Aliphatic index  152.5

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  577.74

Aromaticity  0.125

Average rotatable bonds  3.3125

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  22

X logP energy  -0.8212

Hydropathy 



Literature Information


Title  Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN119040362A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.