SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00434

Signal sequence   MFVFLVLLPLVSS

Length  13

Organism  Artificial

UniProt ID  NA,

Motif  1..13



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00434.cif

Structure  SPKB00434.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1464.86954

Aliphatic index  186.9230769

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  444.19

Aromaticity  0.153846154

Average rotatable bonds  3.384615385

Number of hydrogen bond donors  15

Number of hydrogen bond acceptors  17

X logP energy  1.0976

Hydropathy 



Literature Information


Title  Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN119040362A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.