SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00433

Signal sequence   MKTIIALSYIFCLVLG

Length  16

Organism  Artificial

UniProt ID  NA,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00433.cif

Structure  SPKB00433.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1785.27634

Aliphatic index  170.625

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  586.53

Aromaticity  0.125

Average rotatable bonds  3.625

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -0.3698

Hydropathy 



Literature Information


Title  Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN119040362A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.