SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00431

Signal sequence   MGVKVLFALICIAVAEGVKVLFALICIAVAEGVKVLFALICIAVAEGVKVLFALICIAVAEGVKVLFALICIAVAEA

Length  77

Organism  Artificial

UniProt ID  NA,

Motif  1..77



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00431.cif

Structure  SPKB00431.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7859.93014

Aliphatic index  178.5714286

Isoelectric point  6.280255312

Charge (pH=7)   -0.304488836

Topological polar surface area  2591.52

Aromaticity  0.064935065

Average rotatable bonds  3.38961039

Number of hydrogen bond donors  93

Number of hydrogen bond acceptors  94

X logP energy  -3.9349

Hydropathy 



Literature Information


Title  Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN119040362A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.