SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00430

Signal sequence   MGVKVLFALICIAVAEGVKVLFALICIAVAEGVKVLFALICIAVAEA

Length  47

Organism  Artificial

UniProt ID  NA,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00430.cif

Structure  SPKB00430.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4804.07274

Aliphatic index  176.3829787

Isoelectric point  6.269742076

Charge (pH=7)   -0.183499582

Topological polar surface area  1591.88

Aromaticity  0.063829787

Average rotatable bonds  3.382978723

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  58

X logP energy  -2.4985

Hydropathy 



Literature Information


Title  Signal peptide mRNA for improving expression level of secretory protein and mRNA engineering method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN119040362A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.