SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00421

Signal sequence   TTGKL

Length  5

Organism  Artificial

UniProt ID  NA,

Motif  NA



Activity Information


Pathway  Autocrine

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00421.cif

Structure  SPKB00421.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  518.61084

Aliphatic index  78

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  246.2

Aromaticity  0

Average rotatable bonds  3.4

Number of hydrogen bond donors  9

Number of hydrogen bond acceptors  9

X logP energy  -3.0944

Hydropathy 



Literature Information


Title  Method for secretory expression of conformation signal peptide mediated heterologous protein in escherichia coli

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN118773227A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.