SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00419

Signal sequence   MKATKLVLGAVILGSTLLAC

Length  20

Organism  Saccharomyces cerevisiae DMM1-15A

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00419.cif

Structure  SPKB00419.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2002.54504

Aliphatic index  161

Isoelectric point  9.67623754125088

Charge (pH=7)   1.93541951576338

Topological polar surface area  728.95

Aromaticity  0

Average rotatable bonds  3.4

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -4.78459999999994

Hydropathy 



Literature Information


Title  Defective Escherichia coli signal peptides function in yeast

DOI  10.1111/j.1365-2958.1988.tb00022.x,

Publication Year  1988

PubMed ID  3288832,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.