SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00418

Signal sequence   MDVFKKGFSIADEGVVGAVEKTDQGVTEAAEKTKEGVM

Length  38

Organism  Artificial

UniProt ID  NA,

Motif  1..38



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular vesicles

Secretion efficiency  Increase FAST-PETase activity by 2.1 times

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00418.cif

Structure  SPKB00418.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4002.52134

Aliphatic index  66.57894737

Isoelectric point  4.289906286

Charge (pH=7)   -2.993275804

Topological polar surface area  1692.53

Aromaticity  0.052631579

Average rotatable bonds  3.710526316

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  59

X logP energy  -17.6605

Hydropathy 



Literature Information


Title  Method for improving extracellular secretion expression of plastic degrading enzyme by adopting fusion expression of vesicle signal peptide

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN118652308A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.