SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00416

Signal sequence   MWATLPLLCARAWLL

Length  15

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..15



Activity Information


Pathway  TOM

Natural/Artificial  Natural

Subcellular location  Mitochondria

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00416.cif

Structure  SPKB00416.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1758.21574

Aliphatic index  150

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  575.64

Aromaticity  0.133333333

Average rotatable bonds  3.4

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  20

X logP energy  0.75687

Hydropathy 



Literature Information


Title  Mitochondrial positioning signal peptide and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN118599819A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.