SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00414

Signal sequence   MWATLPLLCARAWLLGVPVCGA

Length  22

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  TOM

Natural/Artificial  Natural

Subcellular location  Mitochondria

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00414.cif

Structure  SPKB00414.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2341.91904

Aliphatic index  133.1818182

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  770.55

Aromaticity  0.090909091

Average rotatable bonds  3.045454545

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  28

X logP energy  -1.81883

Hydropathy 



Literature Information


Title  Mitochondrial positioning signal peptide and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN118599819A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.