SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00399

Signal sequence   HDEL

Length  4

Organism  Artificial

UniProt ID  NA,

Motif  NA



Activity Information


Pathway  Endoplasmic reticulum retention pathway

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00399.cif

Structure  SPKB00399.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  512.51984

Aliphatic index  97.5

Isoelectric point  4.181153034

Charge (pH=7)   -1.908885003

Topological polar surface area  253.9

Aromaticity  0

Average rotatable bonds  4

Number of hydrogen bond donors  8

Number of hydrogen bond acceptors  8

X logP energy  -1.7959

Hydropathy 



Literature Information


Title  Organelle Localized fusion protein

DOI  NA,

Publication Year  2022

PubMed ID  NA,

Patent ID  JP7052977B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.