SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00389

Signal sequence   MGLGKKLSSAVAASFMSLTISLPGVQA

Length  27

Organism  Artificial

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Antigen P54 concentration: 0.47ug/uL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00389.cif

Structure  SPKB00389.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2665.20184

Aliphatic index  108.5185185

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  1027.64

Aromaticity  0.037037037

Average rotatable bonds  3.296296296

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  39

X logP energy  -11.3597

Hydropathy 



Literature Information


Title  Construction and application of engineering bacteria for efficiently guiding secretory expression of African swine fever virus antigen P54 or P30 through two signal peptides

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN118222470A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.