SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00387

Signal sequence   KKIWLAVAGLVLAFSASA

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Penicillin G acylase activity: 9788U/L

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00387.cif

Structure  SPKB00387.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1845.25834

Aliphatic index  146.6666667

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  666.31

Aromaticity  0.111111111

Average rotatable bonds  3.277777778

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  -2.9235

Hydropathy 



Literature Information


Title  Signal peptide for improving penicillin G acylase activity expression, recombinant strain and construction method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN118126133A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.