SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00386

Signal sequence   KKTAIAIAVALAGFATVAQA

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Penicillin G acylase activity: 511U/L

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00386.cif

Structure  SPKB00386.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1915.30664

Aliphatic index  127.5

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  751.81

Aromaticity  0.05

Average rotatable bonds  3.1

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -6.6218

Hydropathy 



Literature Information


Title  Signal peptide for improving penicillin G acylase activity expression, recombinant strain and construction method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN118126133A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.