SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00385

Signal sequence   KYLLPTGAAGLLLLAAQPAMA

Length  21

Organism  Artificial

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Penicillin G acylase activity: 10521U/L

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00385.cif

Structure  SPKB00385.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2083.56014

Aliphatic index  140

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  737.31

Aromaticity  0.047619048

Average rotatable bonds  3.047619048

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  27

X logP energy  -3.7578

Hydropathy 



Literature Information


Title  Signal peptide for improving penicillin G acylase activity expression, recombinant strain and construction method and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN118126133A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.