SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00383

Signal sequence   MQIPQAPWPVVWAVLQLGWRPGW

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5WT9,

Predicted Structure ID  SPKB00383.cif

Structure  SPKB00383.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2716.24444

Aliphatic index  97.39130435

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  922.69

Aromaticity  0.173913043

Average rotatable bonds  3.217391304

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -0.79353

Hydropathy 



Literature Information


Title  Anti-PD-1 signal peptide antibody and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN117858897A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.