SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00382

Signal sequence   MRVTAPRTLILLLSGALALTETWA

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00382.cif

Structure  SPKB00382.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2598.14234

Aliphatic index  142.5

Isoelectric point  10.39777148

Charge (pH=7)   0.9997528

Topological polar surface area  1001.87

Aromaticity  0.041666667

Average rotatable bonds  3.416666667

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  34

X logP energy  -6.87146

Hydropathy 



Literature Information


Title  Tumor vaccine signal peptide for enhancing HLA class I molecular antigen presentation and application thereof

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN117756917A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.